侯可勇,男,博士,教授,博士生导师。
山东省泰山青年学者,山东大学杰出中青年学者
通讯地址:山东省青岛市即墨区滨海路72号山东大学环境研究院K6-332
办公电话:0532-58631956
E-mail:houky@sdu.edu.cn
长期招聘博士后,招聘公告请见:http://www.hj.sdu.edu.cn/info/1018/1949.htm
个人简介:
侯可勇,男,中共党员,博士,教授,博士生导师。主要针对环境污染物实时分析、国家安全需求,从事在线检测质谱新仪器、新方法的研究。作为课题负责人先后主持国家自然科学基金项目4项,国家重大仪器专项课题1项,国家重大研发计划子课题1项,国家"863"资环领域子课题1项,中科院仪器研制项目1项,辽宁省自然科学基金2项。在分析化学、环境领域主流期刊已发表SCI论文70余篇,获得授权的发明专利22项。
主要研究方向:
1.环境污染物现场应急检测新技术及新方法开发和应用;
2.大气自由基及成核关键物种探测新技术及新方法研究;
3.挥发性有机物在线监测及其二次污染机理研究
4.质谱微型化技术及其在国家安全分析中的应用研究。
教育背景:
2002.9-2008.1, 中国科学院大连化学物理研究所,分析化学,博士
1998.7-2002.7, 青岛大学,化学,学士
工作经历:
2019.11-至今,山东大学环境研究院,教授
2016.6-2019.11,中科院大连化学物理研究所,研究员
2013.1-2016.12,中科院青年促进会会员
2011.10-2016.6,中科院大连化学物理研究所,副研究员
2009.10-2011.4, Purdue University,R. Graham Cooks 课题组,博后
2008.1-2009.10,中科院大连化学物理研究所,助理研究员
主持的科研项目:
1. 山东省泰山青年学者基金,2020-2025
2. 山东大学杰出中青年学者基金,2019-2024
3. 国家重大仪器专项课题,“微分迁移谱-飞行时间质谱模块”编号:2013YQ09070302,2013.10-2016.12
4. 国家重大研究计划子课题“易制毒化学品现场鉴定便携热解析质谱技术及应用研究”,编号2016YFC0800902,2016.7-2019.6.30
5. 863资环领域子课题,“低成本高通量环境分析质谱”,编号:2014AA06A501,2014.1.1-2017.12.30
6. 国家自然科学基金面上项目,“面声波电离便携式离子阱质谱路检唾液鉴定毒驾研究”,编号:21874134,2018.1-2021.12
7. 国家自然科学基金面上“离子富集式无窗VUV光电离源及其在便携式TOFMS现场检测VOCs中的应用”,编号:21675155,2017.1-2020.12
8. 国家自然科学基金面上项目,“可快速切换VUV电离和射频增强的化学电离源及其在C2-C12碳氢化合物在线质谱测量中的应用”,编号:21375129,2014.1-2017.12
9. 国家自然科学基金青年基金,水中痕量甲基叔丁基醚(MTBE)及其降解产物的在线质谱检测新方法研究,编号:20907052,2010.1-2012.12
10. 中科院仪器研制项目,“工业VOCs减排技术快速评价装置”,编号:KZCX2-YW-JS402,2010.1-2013.12
11. 辽宁省自然科学优秀人才培育基金,“还原性硫化物在线检测光电子电离迁移谱”,负责人,编号:2014020089,2014.1-2016.12
12. 大连市重点基金,“六氟化硫绝缘全封闭组合电器电气故障在线诊断仪器”,编号:2015A11GX031,2016.1.1-2017.12.30
13. 辽宁省博士启动基金,高灵敏在线质谱水中污染物监测技术,编号:Y034090102, 2009.1-2010.12
参与的科研项目:
1. 国家支撑项目课题,“离子阱质谱的毒品现场查缉和快速鉴定技术与设备的研究”,编号:2013BAK14B04 ,2013.1-2015.12
2. 国家重大仪器专项课题,“超高分辨飞行时间分析器”编号:2011YQ05006904,2011.1-2018.12
发表的主要论文:
1. Chuting,Xu, Weiming,Wang, Shuang Wang,Keyong Hou*,Haiyang Li*, Potential analytical methods for on-site oral drug test: Recent developments and applications, TrAC, 2019, 115649
2. Weiming,Wang, Shuang Wang,Chuting Xu,Hong Li,Yuming Xing,Keyong Hou*,Haiyang Li*, Rapid Screening of Trace Volatile and Nonvolatile Illegal Drugs by Miniature Ion Trap Mass Spectrometry: Synchronized Flash-Thermal-Desorption Purging and Ion Injection,Anal. Chem. 2019,91,10212-10220
3. Shuang Wang, Weimin Wang,Hong Li, Yuming Xing, Keyong Hou,* and Haiyang Li*, Rapid On-Site Detection of Illegal Drugs in Complex Matrix by Thermal Desorption Acetone-Assisted Photoionization Miniature Ion Trap Mass Spectrometer, Anal. Chem., 2019,91,3845-3852
4. Chenxin Wu, Wei Liu,Jichun Jiang, Yan Wang, Keyong Hou *,and Haiyang Li*, An in-source helical membrane inlet single photon ioni-zation time of flight mass spectrometer for automatic monitoring of trace VOCs in water at minutes resolution,Talanta,2019,42,46-51
5. Yan Wang, Lei Hua, Qingyun Li, Jichun Jiang, Keyong Hou, Chenxin Wu, and Haiyang Li *,Direct Detection of Small n-Alkanes at Sub-ppbv Level by Photoelectron-Induced O2+ Cation Chemical Ionization Mass Spectrometry at kPa Pressure,Anal. Chem., 2018, 90 (8), pp 5398–5404
6. Yan Wang, Lei hua, Jichun Jiang, Yuanyuan Xie, Keyong Hou, Qingyun Li, Chenxin Wu and Haiyang Li *, High-pressure photon ionization time-of-flight mass spectrometry combined with dynamic purge-injection for rapid analysis of volatile metabolites in urine. Analytica Chimica Acta. 1008 (2018) 74-81
7. Zhou Lijuan, Jiang Jichun, Zhao Kun, Li Jinxu, Wu Chenxin, Li Haiyang, Tian Di*, Hou Keyong*, “Radiofrequency field enhanced chemical ionization with vacuum ultraviolet lamp for miniature time-of-flight mass spectrometer”. Chinese Chem. Lett., 2018. Volume 29, Issue 5, 707-710
8. Hou Keyong, Li J, Qu T, Tang B, Zhu LP, Huang YG, Li HY*. “Development of a suitcase time-of-flight mass spectrometer for in situ fault diagnosis of SF6‐insulated switchgear by detection of decomposition products”. Rapid Commun. Mass Spectrom., 2016, 30(S1): 38-43.
9. Liu W, Jiang J, Hou Keyong, Weiguo Wang, Yachen Qi, Yan Wang, Yuanyuan Xie, Lei Hua, Haiyang Li *. “Online monitoring of trace chlorinated benzenes in flue gas of municipal solid waste incinerator by windowless VUV lamp single photon ionization TOFMS coupled with automatic enrichment system”. Talanta, 2016, 161: 693-699.
10. Wang Yan, Jiang Jichun, Hua Lei, Keyong Hou, Yuanyuan Xie, Ping Chen, Wei Liu, Qingyun Li, Shuang Wang, and Haiyang Li* , “High-Pressure Photon Ionization Source for TOFMS and Its Application for Online Breath Analysis”. Anal. Chem., 2016, 88(18): 9047-9055.
11. Jichun Jiang, Yan Wang, Keyong Hou, Lei Hua, Ping Chen, Wei Liu , Yuanyuan Xie, Haiyang Li*, “Photoionization-Generated Dibromomethane Cation Chemical Ionization Source for Time-of-Flight Mass Spectrometry and Its Application on Sensitive Detection of Volatile Sulfur Compounds. Anal. Chem. 2016, 88, 5028–5032
12. Yuanyuan Xie, Ping Chen, Lei Hua, Keyong Hou, Yongchao Wang, Haiyan Wang, Haiyang Li*, “Rapid Identification and Quantification of Linear Olefin Isomers by Online Ozonolysis-Single Photon Ionization Time-of-Flight Mass Spectrometry”, J.Am. Soc. Mass Spectrom., 2016, 27(1): 144-152.
13. Wendong Chen, Keyong Hou, Lei Hua, Haiyang Li*, “Dopant-assisted reactive low temperature plasma probe for sensitive and specific detection of explosives”, Analyst, 2015, 140(17): 6025-6030
14. Lei Hua, Keyong Hou, Ping Chen, Yuanyuan Xie, Jichun Jiang, Yan Wang, Weiguo Wang, and Haiyang Li* , “Realization of In-Source Collision-Induced Dissociation in Single-Photon Ionization Time-of-Flight Mass Spectrometry and Its Application for Differentiation of Isobaric Compounds”, Anal. Chem., 2015, 87 (4), pp 2427–2433
15. Chuang Chen, Keyong Hou,Weiguo Wang, Jinghua Li,Haiyang Li*, “Ambient temperature nanoelectrospray ion mobility detector for high performance liquid chromatography in determining amines”, J. Chromatogr. A. 2014; 1358, 192-198.
16. Yuanyuan Xie, Lei Hua, Keyong Hou, Ping Chen, Wuduo Zhao, Wendong Chen, Bangyu Ju, and Haiyang Li*, “Long-Term Real-Time Monitoring Catalytic Synthesis of Ammonia in a Microreactor by VUV-Lamp-Based Charge-Transfer Ionization Time-of-Flight Mass Spectrometry”, Anal. Chem., 2014, 86 (15), pp 7681–7687
17. Wendong Chen, Keyong Hou, Lei Hua, Xingchuang Xiong, Haiyang Li*, “Water-assisted low temperature plasma ionization source for sensitive detection of explosives” , RSC Advances , 2014 , 28, 4, 14791-14794,
18. Ping Chen, Keyong Hou, Lei Hua, Yuanyuan Xie, Wuduo Zhao, Wendong Chen, Chuang Chen, and Haiyang Li*,“Quasi-Trapping Chemical Ionization Source Based on a Commercial VUV Lamp for Time-of-Flight Mass Spectrometry”, Anal. Chem., 2014, 86 (3), pp 1332–1336
19. Shasha Cheng, Weiguo Wang, Qinghua Zhou, Chuang Chen, Liying Peng, Lei Hua, Yang Li, Keyong Hou, and Haiyang Li*, “Fast Switching of CO3–(H2O)n and O2–(H2O)n Reactant Ions in Dopant-Assisted Negative Photoionization Ion Mobility Spectrometry for Explosives Detection”,Anal. Chem., 2014, 86,2687-2693
20. Keyong Hou, Fanglong Li, Wendong Chen, Ping Chen, Yuanyuan Xie , Wuduo Zhao , Lei Hua , Kemei Pei, Haiyang Li* ,“An In-Source Stretched Membrane Inlet for On-Line Analysis of VOCs in Water with Single Photon Ionization TOFMS”, Analyst, 2013,138(17):5826-5831
21. Chen W, Hou Keyong*, Xiong X, Jiang Y, Zhao W, Hua L, Chen P, Xie Y, Wang Z, Li H*. “Non-contact halogen lamp heating assisted LTP ionization miniature rectilinear ion trap: a platform for rapid, on-site explosives analysis”. Analyst, 2013,138(17):5068-73.
22. Shasha Cheng, Jian Dou, Weiguo Wang, Chuang Chen, Lei Hua, Qinghua Zhou, Keyong Hou, Jinghua Li, and Haiyang Li*. “Dopant-Assisted Negative Photoionization IMS for Sensitive Detection of Explosives”, Anal. Chem.,2013, 85, 319−326
23. Xixi Liang, Qinghua Zhou, Weiguo Wang, Xin Wang, Wendong Chen, Chuang Chen,Yang Li, Keyong Hou, Jinghua Li, and Haiyang Li*, “Sensitive Detection of Black Powder by a Stand-Alone Ion Mobility Spectrometer with an Embedded Titration Region”, Anal. Chem.,2013, 85, 4849−4852
24. Qinghao Wu, Lei Hua, Keyong Hou, Huapeng Cui, Haiyang Li*, “Vacuum Ultraviolet Lamp Based Magnetic Field Enhanced Photoelectron Ionization and Single Photon Ionization Source for Online Time-of-Flight Mass Spectrometry”, Anal. Chem., 2011 , Vol 83, 8992-8998
25. Keyong Hou, Wei Xu, R. Graham Cooks*, Zheng Ouyang*, “Sampling Wand for an Ion Trap Mass Spectrometer”, Anal. Chem., 2011, Vol 83 (5), 1857-1861
26. Lei Hua, Qinghao Wu, Keyong Hou*, Huapeng Cui, Ping Chen, Weiguo Wang, Jinghua Li, Haiyang Li*, “Single Photon Ionization and Chemical Ionization Combined Ion Source Based on a Vacuum Ultraviolet Lamp for Orthogonal Acceleration Time-of-Flight Mass Spectrometry”, Anal. Chem. 2011,83(13):5309-5316
27. Chuang Chen, Can Dong, Yongzhai Du, Shasha Cheng, Fenglei Han, Lin Li, Weiguo Wang, Keyong Hou, Haiyang Li*, “Bipolar Ionization Source for Ion Mobility Spectrometry Based on Vacuum Ultraviolet Radiation Induced Photoemission and Photoionization”,Anal. Chem.,2010, Vol 82,4151-4157
授权的主要专利:
1. 侯可勇,董璨,李海洋,“飞行时间质谱仪中真空紫外灯电离装置”,发明专利,专利申请号:200610011793.2 ,2009.4.29授权
2. 侯可勇,李海洋,“一种在线气体分析质谱中的膜进样样品富集装置”,发明专利,专利申请号:200710011223.8 ,2011.12.14授权
3. 侯可勇,李海洋,“微型飞行时间质谱在线样品富集装置”,发明专利,专利申请号:200610134947.7 ,2011.08.31授权
4. 侯可勇,花磊,吴庆浩,崔华鹏,李海洋, “微型质谱仪中空心阴极放电真空紫外光电离源”,发明专利,专利申请号:200910265445.1,2012.11.07授权
5. 侯可勇,陈文东,李海洋,一种添加选择性检测试剂的介质阻挡放电质谱电离源装置,发明专利,201210536370.8,2015.12.09授权
6. 侯可勇,陈文东,崔华鹏,花磊,一种肩背式便携在线分析飞行时间质谱仪,发明专利: 201110233344.3,2015.12.02授权
7. 侯可勇,赵无垛,陈文东,李海洋,一种直线加速型飞行时间质谱中光电离源,发明专利,201210562884.0,2016.03.16授权
8. 侯可勇,崔华鹏,花磊,陈平,李海洋,“一种高灵敏在线分析爆炸物的质谱电离源及其应用”, 发明专利:201110233372.5,2016.03.16授权
9. 侯可勇,李芳龙,陈文东,李海洋,一种在线质谱电离源内管状膜进样装置,发明专利:201210234534.1,2016.06.15授权
10. 侯可勇,花磊,陈平,崔华鹏,李海洋,一种大面积原位检测爆炸物的质谱电离源及其应用,发明专利:201110232457.1,2015.12.16授权
11. 侯可勇,李芳龙,陈文东,李海洋,一种用于在线质谱的直热式管状膜富集进样装置,发明专利:201210234821.2, 2016.12.21授权
12. 侯可勇,苏明扬,李海洋,陈平,蒋吉春,李金旭,一种电离源内螺旋管状膜进样装置,发明专利: 201310694028.5, 2017.1.25授权
国内外学术口头报告:
1. 2015.5.8在武汉召开“中国化学会第十二届全国分析化学年会”报告:在线分析水中VOCs的光电离源内螺旋膜进样质谱方法研究。
2. 2015.7.26 西班牙科尔多瓦,"24th International Conference on Ion Mobility Spectrometry" 报告:"Identification of the characteristic ions of 2-CEES in negative mode by 63Ni ionization source IMS-TOFMS " 。
3. 2015.9.11,北京,现场检测仪器前沿技术研讨会,邀请报告:爆炸物现场检测技术研究。
4. 2015.10.16,在杭州召开“中国化学会第二届全国质谱分析学术报告会”报告:真空紫外光电离源的进展和应用。
5. 2016.8.20,加拿大多伦多, “21st International Mass Spectrometry Conference”,报告:VUV lamp based chemical ionization source for on-situ ion trap mass spectrometry。
6. 2017.6.3 ,美国印第安纳波利斯, 65 th American Society for Mass Spectrometry 年会,报告:Development of an Ultrahigh Resolution Multi-reflection Time-of-Flight Mass Spectrometer for Native Mass Spectrometry。
7. 2017.11.8 ,厦门,第三届全国质谱分析会议,报告:基于真空紫外灯的化学电离微型飞行时间质谱及其应用。
8. 2018年6月,西安会议,中国分析化学会第十三届全国分析化学年会,报告:软电离在线质谱快速分析大气中挥发性有机物。
9. 2018.11.3,青岛,第24届中国大气环境科学与技术大会,报告:汽车中8种VOCs快速在线检测研究。
10. 2018年11月24,广州,中国质谱大会,报告:便携式离子阱质谱及其在毒品现场检测中应用研究。
11. 2019年6月1号,67 th American Society for Mass Spectrometry 年会,报告:Pulse-sampling assisted flash heating desorption miniature ITMS with photoionization for sensitivity and on-site identification of illegal drugs。