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李延伟
作者:   时间:2018-02-01   点击数:

李延伟 博士 副教授 博/硕士生导师

通讯地址:山东省青岛市即墨滨海路72号

办公电话:0532-58631990;E-mail:lyw@sdu.edu.cn

2017/09-至今,山东大学,环境研究院,副教授

2015/11-2016/11,加州大学洛杉矶分校,化学与生物化学系,访问学者,合作导师:Kendall Houk教授

2014/07-2017/09,山东大学,环境研究院,助理研究员

教育背景

2009/09-2014/06,山东大学,环境研究院,博士,导师:张庆竹教授

2005/09-2009/06,山东大学,化学与化工学院,学士

学术兼职:

Sustainability, 编委

Frontiers in Chemistry, 特邀副编辑

PNAS, Applied Catalysis B: Environmental等期刊审稿人

美国化学会会员;中国化学会会员

研究方向:

生物酶作用下环境污染物的催化降解与控制、生物酶作用下环境污染物的催化活化与毒理

毕业学生:

冯姗姗(2018级),去向:山东大学,读博

岳悦(2017级),山东省优秀毕业生,去向:华中科技大学,读博

鲍雷(2016级),去向:中国科学院大学,读博

王小丹(2016级),去向:安徽节源环保科技公司,工作

主持承担的科研项目:

1.国家自然科学基金,面上项目,项目编号:221761112022-2025,负责人

2.国家重点研发计划,绿色生物制造专项,项目编号:2021YFC21036002021-2024,子课题负责人

3.山东大学青年学者未来计划,项目编号:2018WLJH542018-2023,负责人

4.国家科技重大专项,水体污染控制与治理专项,项目编号:2017ZX07202-0022017-2020,子课题负责人

5.国家自然科学基金,重大研究计划重点支持项目,项目编号:916442142017-2020,子课题负责人

6.国家自然科学基金,青年项目,项目编号:215070732016-2018,负责人

7.山东省自然科学基金,培育基金,项目编号:ZR2015PB0022015-2016,负责人

封面文章:

 

近三年主要论文 (#共同第一,*通讯作者):

(1) Mingna Zheng, Yanwei Li*, Weiliang Dong, Shanshan Feng, Qingzhu Zhang, Wenxing Wang. Computational biotransformation of polyethylene terephthalate by depolymerase: A QM/MM approach. Journal of Hazardous Materials, 2022, 127017.

(2) Shanshan Feng, Yanwei Li*, Ruiming Zhang, Qingzhu Zhang, Wenxing Wang. Origin of metabolites diversity and selectivity of P450 catalyzed benzo[a]pyrene metabolic activation. Journal of Hazardous Materials, 2022, 435, 129008.

(3) Mingna Zheng, Yanwei Li,* Weiliang Dong, Weixin Zhang, Shanshan Feng, Qingzhu Zhang, and Wenxing Wang, Depolymerase-Catalyzed Polyethylene Terephthalate Hydrolysis: A Unified Mechanism Revealed by Quantum Mechanics/Molecular Mechanics Analysis, ACS Sustainable Chemistry & Engineering, 2022, 10, 7341.

(4) Junhua Zhou#, Xin Zhang#, Yanwei Li*, Shanshan Feng, Qingzhu Zhang, Wenxing Wang, Endocrine-Disrupting Metabolic Activation of 2-Nitrofluorene Catalyzed by Human Cytochrome P450 1A1: A QM/MM Approach. Environment International, 2022, 107355.

(5) Yue Yue#, Jiaqian Fan#, Guoqing Xin, Qun Huang, Jian-bo Wang*, Yanwei Li*, Qingzhu Zhang, Wenxing Wang. Comprehensive Understanding of Fluoroacetate Dehalogenase-Catalyzed Degradation of Fluorocarboxylic Acids: A QM/MM Approach. Environmental Science & Technology, 2021, 55, 9817−9825. (Featured Cover Article)

(6) Shanshan Feng, Yue Yue, Mingna Zheng, Yanwei Li*, Qingzhu Zhang,  Wenxing Wang. IsPETase- and IsMHETase-Catalyzed Cascade Degradation Mechanism toward Polyethylene Terephthalate. ACS Sustainable Chemistry & Engineering, 2021, 9, 9823–9832.

(7) Pijun Duan, Xinning Liu, Binhua Liu, Muhammad Akram, Yanwei Li*, Jingwen Pan, Qinyan Yue, Baoyu Gao, XingXu*. Effect of phosphate on peroxymonosulfate activation: Accelerating generation of sulfate radical and underlying mechanism. Applied Catalysis B: Environmental, 2021, 298, 120532.

(8) Chen Yang#, Zitong Liu#, Yanwei Li#, Shuyao Zhou, Chenxi Lu, Yilin Guo, Melissa Ramirez, Qingzhu Zhang, Yu Li, Zhirong Liu, K. N. Houk*, Deqing Zhang*, Xuefeng Guo*. Electric field–catalyzed single-molecule Diels-Alder reaction dynamics. Science Advances, 2021, 7, eabf0689.

(9) Hongxia Zhang#, Shaixiao Tian#, Yue Yue, Min Li, Wei Tong, Guangyu Xu, Bo Chen, Ming Ma, Yanwei Li*, and Jian-bo Wang*. Semirational design of fluoroacetate dehalogenase RPA1163 for kinetic resolution of αfluorocarboxylic acids on a gram scale. ACS Catalysis, 2020, 10, 31433151.

(10) Pijun Duan, Yuanfeng Qi, Shanshan Feng, Xiaoming Pengd Wei Wang, Yue Yue,Yanan Shang, Yanwei Li*, Baoyu Gao, Xing Xu*. Enhanced degradation of clothianidin in peroxymonosulfate/catalyst system via core-shell FeMn @ N-C and phosphate surrounding. Applied Catalysis B: Environmental, 2020, 267, 118717. (Highly Cited Paper)

(11) Yue Yue, Jinfeng Chen, Lei Bao, Junjie Wang, Yanwei Li*, Qingzhu Zhang. Fluoroacetate dehalogenase catalyzed dehalogenation of halogenated carboxylic acids: A QM/MM approach. Chemosphere, 2020, 254, 126803.

(12) Shanshan Feng, Yue Yue, Jinfeng Chen, Jie Zhou, Yanwei Li*, Qingzhu Zhang. Biodegradation mechanism of polycaprolactone by a novel esterase MGS0156: a QM/MM approach. Environmental Science: Processes & Impacts, 2020, 22, 2332–2344. (Featured Cover Article)

(13) Yanwei Li*, Yue Yue, Hongxia Zhang, Zhongyue Yang, Hui Wang, Shaixiao Tian, Jian-bo Wang*, Qingzhu Zhang*, Wenxing Wang. Harnessing fluoroacetate dehalogenase for defluorination of fluorocarboxylic acids: in silico and in vitro approach. Environment International, 2019, 131, 104999.

(14) Xiaodan Wang, Jinfeng Chen, Xiaowen Tang, Junjie Wang, Ledong Zhu, Weixin Zhang, Hui Wang, Yanwei Li*, Qingzhu Zhang. Biodegradation mechanism of polyesters by hydrolase from Rhodopseudomonas palustris: An in silico approach. Chemosphere, 2019, 221, 1120.

(15) Lei Bao, Wen Liu, Yanwei Li*, Xueyu Wang, Fei Xu, Zhongyue Yang, Yue Yue, Chenpeng Zuo, Qingzhu Zhang* and Wenxing Wang, Carcinogenic Metabolic Activation Process of Naphthalene by the Cytochrome P450 Enzyme 1B1: A Computational Study. Chemical Research in Toxicology, 2019, 32, 603-612.

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